Back to top

Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation

Daily Dose 2011-01-21 0 comments

By Brett |  Published in Marijuana Saves Lives

This review covers reports published in the last 5 years on the anti-inflammatory activities of all classes of cannabinoids, including phytocannabinoids such as tetrahydrocannabinol and cannabidiol, synthetic analogs such as ajulemic acid and nabilone, the endogenous cannabinoids anandamide and related compounds, namely, the elmiric acids, and finally, noncannabinoid components of Cannabis that show anti-inflammatory action.

It is intended to be an update on the topic of the involvement of cannabinoids in the process of inflammation. A possible mechanism for these actions is suggested involving increased production of eicosanoids that promote the resolution of inflammation.

This differentiates these cannabinoids from cyclooxygenase-2 inhibitors that suppress the synthesis of eicosanoids that promote the induction of the inflammatory process.

The Marijuana Saves Lives Foundation is a grassroots non-profit, working off of charitable donations and t-shirts sales. They are dedicated to changing the negative stigma that is associated with marijuana and believes change will come from the truth.