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CB1 Receptor

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The Endocannabinoid System
Daily Dose 2015-01-06

The Endocannabinoid System

Dr. Christina Sanchez Talks About the Endocannabinoid System Vimeo Description: Dr. Christina Sanchez is…

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Can Cannabinoids Kill Tumors While Leaving Healthy Cells Alone?
Sam Sabzehzar 2013-07-06

Can Cannabinoids Kill Tumors While Leaving Healthy Cells Alone?

By Dr. Michelle Sexton, N.D. An Egyptian manuscript known as “Fayyum Medical Book” compiled…

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University of Saskatchewan Researchers Discover Cannabis “Pharma Factory”
Sam Sabzehzar 2013-03-23

University of Saskatchewan Researchers Discover Cannabis “Pharma Factory”

By Michael Robin  |  Published in USASK.CA University of Saskatchewan researchers have discovered the chemical…

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Daily Dose 2010-11-29

Medical Marijuana: A Plant Medicine Explained

Marijuana is derived from leaves and dried flowering tops of the plant cannabis sativa. Marijuana is not a single drug. Cannabis sativa contains over 400 chemicals.

The plant is very adaptive to its surroundings which allows the plant to have more variable characteristics than most plants. Scientific research on the pharmacology of marijuana is sometimes uncertain or inconsistent because of the varying potency of the plants.

The use of research subjects who have a wide variety of experience with marijuana also contributes to variances in marijuana study data

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Osteoporosis
Daily Dose 2010-05-07

Osteoporosis

These two receptors that are specific to cannabinoids. But cannabinoids also, some of them bind to other receptors. There is one-called 133 I think, GPR133, there is another one, which is GPR18. I may be mistaken on the numbers, but I think GPR18, GPR133 and so on. They are not specific for the cannabinoids so there is a lot of discussion between the pharmacologists should we call them cannabinoid receptors. The decision at the moment is lets wait and sees. At the moment we have only two that have been approved as cannabinoid receptors. All the others with a question mark. Two receptors have evolved for certain specific conditions, feeding for example, appetite, feeding, and things of that sort. But some of the other actions most definitely go through other systems.

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Dr. Raphael Mechoulam
Daily Dose 2010-05-07

Dr. Raphael Mechoulam

Endocannabinoids this is the short name for endogenous cannabinoids. Cannabinoids is a compound, which acts on two receptors. One receptor is found mainly in the brain, the other receptor is found mainly in the periphery. But, surprisingly, or maybe not so surprisingly, during certain diseases the second receptor that is not present in the brain starts to pop up. All of a sudden it is available there. So the suggestion has been made by many others, and us that actually this receptor, the Cb2 receptor, is part of a protective mechanism. We have protective systems in our body. The immune system is a protective system. It guards us against microbes and viruses things like that. If we didnt have an immune system, we would be dead in a week. Probably eaten up by microbes.

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Endocannabinoid System - Vital Role In Human Body
Daily Dose 2010-04-08

Endocannabinoid System - Vital Role In Human Body

Science has found two cannabinoid receptors, CB1 and CB2 (so far) as part of our ‘receptor’ category within the human endocannabinoid system but with further research we’ll soon begin to understand much more about this system (internal compounds much like marijuana). This system also includes degradation, synthesis, and transport. Some of these compounds date back roughly 600 million years and can be found in hundreds of life forms and it is through these life forms that this system evolved with us.

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David Bearman - Medicinal Benefits of Cannabis
Daily Dose 2010-04-02

David Bearman - Medicinal Benefits of Cannabis

There are a group of researchers around the world, that are very interested in the endocannabinoid system, interested in how that works, how it functions. Elger is one of those people. He and another PHD named Nichol wrote an article that appeared in Scientific America which I believe is entitled The Brains on Marijuana. We have discovered, we meaning scientists not me, at least two endocannabinoids, two different 21 carbon molecules that have receptor sites that can be stimulated by Cannabis. And Cannabis of course, has 66, at least 66 cannabinoids and those are 21 carbon molecules that may have different side chain and every time you have a different side chain you have a different substance.

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