Endocannabinoid System Guide

Endocannabinoid System

Science has found two cannabinoid receptors, CB1 and CB2 (so far) as part of our ‘receptor’ category within the human endocannabinoid system but with further research we’ll soon begin to understand much more about this system (internal compounds much like marijuana). This system also includes degradation, synthesis, and transport.  Some of these compounds date back roughly 600 million years and can be found in hundreds of life forms and it is through these life forms that this system evolved with us.

The endocannabinoid system acts as a regulator, constantly attempting to bring our bodies back to equilibrium. Our endocannabinoid system helps us maintain homeostasis, control basic processes like glucose metabolism and other metabolic processes, and “regulate intercellular communication, especially within the immune and nervous systems,” according to Harm Reduction Journal.

In General, cannabinoids modulate and coordinate tissues, organ, and body systems, including cardiovascular, digestive, endocrine, excretory, musculo-skeletal, reproductive, and respiratory systems.  The effects of cannabinoids on consciousness are not well understood, but are well known, and underlie the popular recreational use of the plant.  These effects also have therapeutic possibilities.

CANNABONOID GUIDE

Sources:

Brown TT, Dobs AS: Endocrine effects of marijuana.

J Clin Pharmacol 2002, 42:90S-96S.

Habayeb OM, Bell SC, Konje JC: Endogenous cannabinoids: metabolism and their role in reproduction.

Life Sci 2002, 70:1963-1977. PubMed Abstract | Publisher Full Text

De Petrocellis L, Melck D, Bisogno T, Milone A, Di Marzo V: Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response. Neuroscience 1999, 92:377-387. | Publisher Full Text

Dmitrieva N, Berkley KJ: Contrasting effects of WIN 55212-2 on motility of the rat bladder and uterus.

J Neurosci 2002, 22:7147-7153.

Grotenhermen F, Muller-Vahl K: IACM 2nd Conference on Cannabinoids in Medicine.

Expert Opin Pharmacother 2003, 4:2367-2371. | Publisher Full Text

Guzman M, Sanchez C: Effects of cannabinoids on energy metabolism.Life Sci 1999, 65:657-664. | Publisher Full Text

Habayeb OM, Bell SC, Konje JC: Endogenous cannabinoids: metabolism and their role in reproduction.

Life Sci 2002, 70:1963-1977. | Publisher Full Text

Hiley CR, Ford WR: Endocannabinoids as mediators in the heart: a potential target for therapy of remodelling after myocardial infarction?

Br J Pharmacol 2003, 138:1183-1184. | Publisher Full Text

Pinto L, Izzo AA, Cascio MG, Bisogno T, Hospodar-Scott K, Brown DR, Mascolo N, Di Marzo V, Capasso F: Endocannabinoids as physiological regulators of colonic propulsion in mice. Gastroenterology 2002, 123:227-234. | Publisher Full Text

Ralevic V: Cannabinoid modulation of peripheral autonomic and sensory neurotransmission. Eur J Pharmacol 2003, 472:1-21. | Publisher Full Text

Rottanburg D, Robins AH, Ben-Arie O, Teggin A, Elk R: Cannabis-associated psychosis with hypomanic features.

Lancet 1982, 2:1364-1366. | Publisher Full Text

Yuan M, Kiertscher SM, Cheng Q, Zoumalan R, Tashkin DP, Roth MD: Delta 9-Tetrahydrocannabinol regulates Th1/Th2 cytokine balance in activated human T cells. J Neuroimmunol 2002, 133:124-131.

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